New anti-clotting agent has its own 'off switch'
The anticoagulant's anti-clotting action can be rapidly stopped on demand, which could enable new surgical and post-operative drugs that minimise the risk of serious...
Genetic cause found for rare neurological disease
The progressive neurological disease known as spinocerebellar ataxia 4 (SCA4) is a rare movement disorder with no known cure and, until recently, no known cause.
One-two punch treatment knocks out acute myeloid leukaemia
Researchers paired venetoclax, a current standard-of-care anticancer drug for acute myeloid leukaemia, with a STING agonist, an emerging class of immunotherapy drug.
Creating self-assembling capsules for drug delivery
Scientists have created nanosized capsules that could be used to deliver drugs and messenger RNA (mRNA), a molecule that instructs cells to produce proteins.
Researchers find the 'switch' that deactivates brown fat
Researchers have found a protein that is responsible for turning off brown fat activity, in a breakthrough which could help to address obesity and related health problems.
One-two punch treatment knocks out acute myeloid leukaemia
Researchers paired venetoclax, a current standard-of-care anticancer drug for acute myeloid leukaemia, with a STING agonist, an emerging class of...
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Creating a genetic medicine manufacturing ecosystem: part 5
When it comes to the mission to democratise medicine, Australia has a material opportunity to...
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$50m grant to power Artificial Heart Frontiers Program
The MRFF-funded Artificial Heart Frontiers Program will seek to develop and commercialise three...
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Successful embryo transfer could save rhinos from extinction
The successful embryo transfer and pregnancy of a southern white rhino allow researchers to...
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Melatonin helps to prevent obesity, studies suggest
In an experiment carried out in rats, chronic administration of melatonin prevented obesity to a greater extent than acute treatment and reduced...
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Pig hearts kept alive outside the body for 24 hours
A major hurdle for human heart transplantation is the limited storage time of the donor heart...
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Maternal obesity may promote liver cancer in offspring
The offspring of obese female mice were found to have an 80% risk of developing cancer, compared...
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Certain hormone drugs linked to increased brain tumour risk
Prolonged use of certain progestogen hormone drugs has been associated with an increased risk of...
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New targets identified for a universal influenza B vaccine
Researchers have identified fragments from influenza B viruses that the immune system consistently recognise, offering promising targets for a...
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Breakthrough antibiotic for mycobacterial infections
The antibiotic candidate, named COE-PNH2, has been optimised to target Mycobacterium...
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A new pathway for reversible male birth control
Most experimental male birth control drugs use a hammer approach to block sperm production, but...
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Zika virus vaccine used to battle brain cancer
Scientists at Duke-NUS Medical School have found a way to use the Zika virus to destroy brain...
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Researchers find the 'switch' that deactivates brown fat
Researchers have found a protein that is responsible for turning off brown fat activity, in a breakthrough which could help to address obesity and...
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Personality influences the expression of our genes
An international research team has used artificial intelligence to show that our personalities...
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CRISPR-Cas gene editing eliminates HIV in lab
Scientists deployed CRISPR-Cas molecular scissors and two gRNAs against 'conserved' HIV...
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Protein biomarkers help predict dementia 15 years in advance
A new study adds to the growing body of evidence that measuring levels of certain proteins in the...
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Self-driving needle steers its way through living lung tissue
Researchers have built a compact robotic system that can autonomously steer a flexible needle around anatomical obstacles within the lungs of live...
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The ups and downs of DIY lab automation
While developing lab automation in-house might seem attractive at first glance, the road is...
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Can AI replicate the human touch in healthcare provision?
There are already some encouraging signs of AI's potential to change the world of public...
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Can AI fix the life sciences reproducibility crisis?
Researchers may be able to address the reproducibility crisis in the future by using AI to...
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